Crystal structure of HCV NS3/4A protease variant Y56H in complex with MK-5172
收藏Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
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Crystal structure of HCV NS3/4A protease variant Y56H in complex with MK-5172 Descriptor: (1aR,5S,8S,10R,22aR)-5-tert-butyl-N-{(1R,2S)-1-[(cyclopropylsulfonyl)carbamoyl]-2-ethenylcyclopropyl}-14-methoxy-3,6-di oxo-1,1a,3,4,5,6,9,10,18,19,20,21,22,22a-tetradecahydro-8H-7,10-methanocyclopropa[18,19][1,10,3,6]dioxadiazacyclononadec ino[11,12-b]quinoxaline-8-carboxamide, NS3 protease, SULFATE ION, ... Authors: Matthew, A.N, Schiffer, C.A. Deposit date: 2018-01-08 Release date: 2019-01-16 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.859 Å) Cite: Clinical signature variant of HCV NS3/4A protease uses a novel mechanism to confer resistance To Be Published
创建时间：
2018-01-08
