InsP6-induced autoprocessing CGTs and MARTX toxins.

aBased on analysis of effector domains as reviewed in [15], [22].bProcessing site is indicated by inverted arrow. m, processing site as mapped experimentally by N-terminal sequencing or mass spectrometry; p, processing site predicted by homology to mapped processing site from closely related toxin; a, alternative processing site identified by mass spectrometry. Numbering of MARTXVc processing sites is based on amino acid sequence as originally annotated in [37] and may be different than that found in cited references. For other MARTX toxins, not all processing sites are known and only those previously reported in the literature are listed.