The expression level of miRNAs in Control-EXO and RIPC-EXO

To explore the possibility of miRNA(s) contributing to the cardioprotection induced by plasma exosomes at the late phase of RIPC, we performed a miRNA profiling assay (763 rat miRNAs) comparing the differences between RIPC-exo and Control-exo using Illumina HiSeq 2500 high-throughput sequencing.为探究微小RNA（microRNA, miRNA）在远程缺血预处理（Remote Ischemic Preconditioning, RIPC）晚期阶段血浆外泌体诱导的心脏保护作用中所发挥的潜在作用，我们采用Illumina HiSeq 2500高通量测序平台，针对763种大鼠miRNA开展miRNA表达谱分析，对比远程缺血预处理组外泌体（RIPC-exo）与对照组外泌体（Control-exo）之间的表达水平差异。