MLL1 is essential for retinal development
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https://www.ncbi.nlm.nih.gov/sra/SRP131314
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资源简介：
By removing MLL1 from mouse retinal progenitors, we discovered that MLL1 plays multiplex roles in retinal development by regulating: 1) progenitor cell proliferation and cell cycle progression; 2) retinal cell composition; 3) maintenance of horizontal neurons; 4) formation of functional synapses between neuronal layers; and 5) visual function development. Altogether, our results suggest that MLL1 is an indispensable regulator for the development of retinal structure and function. Overall design: Triplicate mutant (MLL1 fl/fl Chx10-Cre) and triplicate WT samples were compared
创建时间：
2018-08-16
