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Innate Immune Activation by and Antiviral Activity of DMXAA.

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Figshare2016-02-23 更新2026-04-29 收录
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https://figshare.com/articles/dataset/_Innate_Immune_Activation_by_and_Antiviral_Activity_of_DMXAA_/1621540
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A. Immunoblot of lysates from murine RAW264.7 cells following exposure to 100μM DMXAA for indicated time showing phosphorylation status of IRF3 S386, total IRF3, and GAPDH. (B) mRNA synthesis of indicated genes in RAW264.7 cells following 8h exposure to indicated concentration of DMXAA. Values represent average mRNA fold change ±SD from duplicate experiments relative to cells exposed to 1% DMSO. (B) Levels of serum-associated CHIKV at 72h post infection. Five mice per group were treated with DMSO alone or DMXAA at 3h pre- or 6h or 24h post inoculation as indicated.
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2016-02-23
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