PI3Kdelta in complex with an inhibitor
收藏Protein Data Bank Japan2024-01-31 更新2026-04-19 收录
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PI3Kdelta in complex with an inhibitor Descriptor: (4~{S})-3-[6-[2-azanyl-4-(trifluoromethyl)pyrimidin-5-yl]-2-morpholin-4-yl-pyrimidin-4-yl]-4-methyl-1,3-oxazolidin-2-one, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform Authors: Gutmann, S, Rummel, G, Shrestha, B. Deposit date: 2022-02-04 Release date: 2022-05-18 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Identification of NVP-CLR457 as an Orally Bioavailable Non-CNS-Penetrant pan-Class IA Phosphoinositol-3-Kinase Inhibitor. J.Med.Chem., 65, 2022
创建时间：
2022-02-04
