Endometrial transcriptomic profiles in patients with severe IUA and normal control

Intrauterine adhesion (IUA) is characterized by endometrial fibrosis with partial or complete uterine cavity obliteration. IUA patients often undergo amenorrhea/ hypomenorrhea, abdominal pain, infertility, early pregnancy loss or severe placental complications. In this work, endometria samples were collected from severe IUA and control patients. RNA-seq was performed to identify differences between IUA and normal control and investigate the mechanisms of IUA development. Endometria samples from 7 severe IUA patients (Ba) and 7 normal controls (Con)