Bulk transcriptome analysis of conditional MYT1L-mutant ESC-derived human induced neurons.
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE171324
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资源简介：
We examined the effect of heterozygous MYT1L deficiency in human induced neurons. Increased expression of genes with MYT1L binding motifs and activation of non-neuronal genes were observed in human neurons along with deregulation of autism-associated risk genes upon depletion of MYT1L. Bulk RNA sequencing of MYT1L (+/flox) ESC-derived human induced neurons upon cre-mediated depletion (+/-) compared to delta-cre transduced isogenic controls, 7 or 43 days after NGN2-mediated induced neurogenesis.
创建时间：
2023-05-17
