Neuropsychological Raw and Z scores at Baseline and Follow-up Visits.

Mean±SD; FU(follow-up) vs baseline, *p<0.05, **p<0.01; Annual change = (FU-baseline)/years followed. Annual change% = (Annual change/baseline score)*100%.
MMSE: mini-mental status examination; AVLT: auditory verbal learning test; LM: logic memory test; Stroop: Stroop color word test; CFT: complex figure test; VFT: verbal fluency test; TMT: trail making test; CDT: clock drawing test; FPT: five point test; HNT: Huashan naming test. Zmem: Z score of memory; Zexe: Z score of executive function; Zvisuo: Z score of visuo-spatial function; Zlang: Z score of language; Zatt: Z score of attention function; Ztotal: Z score of global cognition.