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Inherent Motor Impulsivity Associates with Specific Gene Targets in the Rat Medial Prefrontal Cortex

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP233373
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The present study profiled the complete set of mRNA expressed from genes (transcriptome) in the medial prefrontal cortex of male, outbred rats stably expressing high (HI) or low (LI) motor impulsivity identified in the 1-choice serial reaction time (1-CSRT) task. Overall design: HI and LI rats were defined as falling within the upper and lower quartiles of premature responses in the 1-CSRT task (n = 4-6/phenotype), respectively. RNA-sequencing was performed on isolated mPFC homogenate. Gene expression differences in HI vs. LI rats were identified using Fisher's exact test (a = 0.1).
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2021-02-26
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