Gene expression analysis of the hippocampus in Il18+/+ and Il18-/- mice at 12 weeks of age
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE108485
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Interleukin-18 (IL-18) was one of the inflammatory cytokines and related to major depressive disorder (MDD) and dementia. Compared with Il18+/+ mice, IL-18 knockout (Il18−/−) mice developed impaired learning and memory, more anxiety, and less motivation. To reveal the mechanism, the microarray was performed. The hippocampus of mice Il18+/+ and Il18-/- C57BL/6 N mice at 12 weeks of age was extracted. We mixed tatal RNA from 7 mice prefrontal cortex per each.
创建时间:
2020-01-01



