The role of the c-Jun N-terminal kinase pathway at the interface between reproduction and immunity. Repro-Immunity

n Anopheles gambiae mosquitoes the c-Jun N-terminal kinase (JNK) pathway is pivotal in anti-plasmodium immunity. While the JNK pathway has an established role in Anopheles immunity, especially in the context of P. berghei infection (1), its participation in the control of reproductive functions such as oviposition and egg development has not been addressed. This project seeks to identify molecular targets of the JNK pathway that regulate oviposition and egg development and sit at the interface between immunity and reproductive fitness,