Reduced Airway Surface pH Impairs Bacterial Killing in the Porcine Cystic Fibrosis Lung

ChEBI2012-03-29 更新2026-07-21 收录

囊性纤维化病原

气道微生物免疫

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Reduced Airway Surface pH Impairs Bacterial Killing in the Porcine Cystic Fibrosis Lung

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2012-03-29

A single cell atlas of the airway epithelium reveals the CFTR-rich pulmonary ionocyte

单细胞转录组学

囊性纤维化病原

The functions of epithelial tissues are dictated by the types, abundance, and distribution of the differentiated cells they contain. Attempts to restore tissue function after damage require knowledge

NIAID Data Ecosystem120

Cystic fibrosis Airway primary epithelial cells in air-liquid interrface culture show abnormal inflammation and lipid metabolism related RNA expresssion compared to non-CF

囊性纤维化病原

脂质代谢

A deficiency in cystic fibrosis transmembrane conductance regulator (CFTR) function in cystic fibrosis (CF) leads to chronic lung disease. However, the molecular mechanisms are not well understood and

NIAID Data Ecosystem40

Supplemental information: The airway epithelial muco-inflammatory response to IL-13 is exacerbated in cystic fibrosis

囊性纤维化病原

气道炎症反应

Supplemental materials and methods for The airway epithelial muco-inflammatory response to IL-13 is exacerbated in cystic fibrosis.

NIAID Data Ecosystem20

Metaproteomic analysis of gut microbiota from 30 samples of cystic fibrosis infants

微生物宏蛋白质组学

囊性纤维化病原

The link between human gut microbiota (a complex group of microorganisms including not only bacteria but also fungi, viruses, etc.,) and the physiological state is nowadays unquestionable. Metaproteom

NIAID Data Ecosystem60

Single cell RNAseq reveals a critical role of chloride channels in airway development. Mus musculus, Homo sapiens

发育生物学

囊性纤维化病原

The conducting airway for air passage forms a protective mucosal barrier, and presents the primary target of various airway disorders. To better understand how the airway developmental programs are es

NIAID Data Ecosystem20

Reduced Airway Surface pH Impairs Bacterial Killing in the Porcine Cystic Fibrosis Lung

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