MTF1
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https://rgd.mcw.edu/rgdweb/report/gene/main.html?id=1319031
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This gene encodes a transcription factor that induces expression of metallothioneins and other genes involved in metal homeostasis in response to heavy metals such as cadmium, zinc, copper, and silver. The protein is a nucleocytoplasmic shuttling protein that accumulates in the nucleus upon heavy metal exposure and binds to promoters containing a metal-responsive element (MRE). [provided by RefSeq, Jul 2008]
本基因编码一种转录因子，该因子可诱导金属硫蛋白及其他参与金属稳态的基因在应对重金属如镉、锌、铜和银等时表达。该蛋白质是一种核质穿梭蛋白，在重金属暴露后聚集于细胞核，并与含有金属反应元件（MRE）的启动子结合。[提供者：RefSeq，2008年7月]
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