FGFR2 Kinase Domain Bound to Irreversible Inhibitor Cmpd 10
收藏Protein Data Bank Japan2024-10-23 更新2026-04-19 收录
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FGFR2 Kinase Domain Bound to Irreversible Inhibitor Cmpd 10 Descriptor: Fibroblast growth factor receptor 2, GLYCEROL, N-[4-(4-amino-7-methyl-5-{4-[(4-methylpyrimidin-2-yl)oxy]phenyl}-7H-pyrrolo[2,3-d]pyrimidin-6-yl)phenyl]-2-methylpropanamide, ... Authors: Valverde, R, Foster, L. Deposit date: 2023-08-31 Release date: 2024-02-14 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (3.33 Å) Cite: Discovery of lirafugratinib (RLY-4008), a highly selective irreversible small-molecule inhibitor of FGFR2. Proc.Natl.Acad.Sci.USA, 121, 2024
创建时间：
2023-08-31
