Histomorphological Analysis of Polyps of Gastrointestinal TractA Retrospective Study from A Tertiary Care Centre

Introduction: Polyps are more common in colorectal region of total gastrointestinal (GI)tracts. Even though most of the polyps are benign, neoplastic polyps derives significant attention. Understanding the prevalence, distribution and morphological types will improve the screening and treatment strategy. Aim of this study is to analyse the polyp specimens that were presented in our Institute. Materials and Methods: This is a retrospective study done in our Institute between January 2022 to December 2022. The study included the polyps and polypoidal lesions of gastrointestinal tract either received as biopsy, polypectomy, or resected specimens. Ulcers and frank malignant lesions were excluded from the study. Results: Total number of GI specimens received in the study period were 2541, among them 131 were polyp specimens and that were taken into analysis. Median age of the study population was 56 (range 16-98 years), commonest decade was 5th decade. Males has more prevalence than females (ratio 1.75:1). Large intestine was the common site for polyps and serrated lesions were more common morphological type. Most of the serrated and adenomatous polyps were associated with dysplasia. Malignant polyps were squamous cell carcinoma, adeno carcinoma and Lymphoma. Intestinal polyposis noted in few cases. Conclusion: Polyps are increasing in their incidence. Colorectum was the common region involved. Now serrated lesion were more commonly noted and they were almost associated with dysplasia.