Genetic and Epigenetic Regulation of Skeletal Muscle Ribosome Biogenesis with Exercise
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https://www.ncbi.nlm.nih.gov/sra/SRP308449
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资源简介:
Ribosomes are the macromolecular engines of protein synthesis. Factors mediating ribosome biogenesis in skeletal muscle that facilitate adaptation to exercise are multi-factorial, but may be related to ribosomal DNA (rDNA) dosage and/or epigenetic modifications to rDNA. To investigate these possibilities, we conducted whle genome sequencing (WGS) on skeletal muscle biopsies from human subjects to computationally estimate rDNA dosage.
创建时间:
2021-08-06



