Bioassay-guided fractionation of a methanol extract of the seeds of Caesalpinia sappan led to the isolation of 12 new cassane-type diterpenes, caesalsappanins A–L (1–12). Their structures were elucida

NIAID Data Ecosystem90

EC 50 and EC 90 values (µM) for 4-aminoquinoline derivatives tested in viral pseudotype entry and viral replication assays.

抗病毒药物

活性测试

aCQ: Chloroquine; bHQ: Hydroxychloroquine; cAMD: Amodiaquine; dAQ-13: Aminoquinoline-13.

NIAID Data Ecosystem70

新化合物结构

新型化合物

活性测试

均为吲哚类生物碱，测试了抗破骨细胞分化活性，15个化合物具有显著的抗破骨细胞分化活性

南海海洋数据中心100

F6037-0164 Inhibition Assay

药物抑制实验

胞外酶活性测定

IC50 determination on KAT-II for F6037-7280

Figshare2018-01-15 更新70