GLP-1 receptor agonist exposures reported to U.S. poison centers, 2012–2023 (NPDS data and R analysis code)
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# GLP-1 receptor agonist exposures reported to US poison centers (2012–2023) Version: v1.0License: CC BY 4.0 (data, code, and figures) Contents- APC NPDS Extended GLP-1 Data.xlsx - raw extended NPDS dataset (multiple worksheets by domain: demographics, clinical effects, therapy, etc.)- GLP1 Preprocessing V2 copy3.Rmd - preprocessing pipeline (harmonization, recoding, integration across worksheets, export of preprocessed data)- Joined_Preprocessed_GLP1_Data.xlsx - cleaned, integrated dataset produced by preprocessing step- GLP1 Data Exploration copy4.Rmd - exploratory summaries, frequencies, preliminary figures- GLP1 Demographics Table calcs.Rmd - code for demographics, exposures by reason/site, outcomes, and effect duration tables- GLP1 Modelling.Rmd - time-series and regression modeling (polynomial, Poisson, negative binomial, LASSO/elastic net) Environment: - R version: 2025.05.1 (Build 513)- Required packages: tidyverse, readxl, openxlsx, writexl, MASS, mgcv, glmnet, coin, mice, ggtext, patchwork, gt, webshot2, magick, gridExtra.- Conflicts resolved using: conflicted (select and filter set to dplyr defaults). Instructions for reproduction:1. APC NPDS Extended GLP-1 Data2. GLP1 Preprocessing V2 copy33. Joined_Preprocessed_GLP1_Data4. GLP1 Data Exploration copy45. GLP1 Demographics Table calcs6. GLP1 Modelling (Poisson regression) Notes- Records are de-identified (no case numbers, free text, or exact dates). CitationFor the current citation and DOI, see the Zenodo landing page “cite as”. ContactRobert Miller — MillerRS@uthscsa.edu
