Extracellular vesicles from Staphylococcus aureus-infected alveolar macrophages induce necroptosis

Staphylococcus aureus (S. aureus), a major cause of hospital and community-acquired pneumonia, still has a high mortality rate. Extracellular vesicles (EVs), as crucial mediators of intercellular communication, have a significant impact on infectious diseases. However, the role of EVs from alveolar macrophages (AMs) in S. aureus pneumonia remains unclear.