Biologic parameters for modeling of SIV-specific CD8+ T lymphocyte compartment.
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The biological constants utilized for modeling of SIV-specific CTLs are listed.*Based on Sopper et al describing a total body number of 3.5×109 CD8+ T lymphocytes and Blattman et al demonstrating the frequency of epitope precursors to be 5×10−6, and assuming a persisting CTL response to 5 epitopes.**Derived constant calculated from biologically observed steady state value for total body CTLs, frequency of epitope-specific CTLs and loss rate of epitope-specific CTLs (see Supplemental Methods).
创建时间：
2015-12-02
