Anthracycline treatment and resistance in four human cancer cell lines (HGU133A)

ChEBI2010-04-27 更新2026-07-21 收录

肿瘤耐药机制

癌症药物敏感性

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Anthracycline treatment and resistance in four human cancer cell lines (HGU133A)

创建时间：

2010-04-27

AZ1366: An inhibitor of tankyrase and the canonical Wnt pathway that limits the persistence of non-small cell lung cancer cells following EGFR inhibition. Homo sapiens

肿瘤耐药机制

组合治疗

EGFR-mut NSCLC lines show differential suceptibility to inhibition of tankyrase in the presence of EGFR inhibitors Overall design: NSCLC cells were treated in quadruplicate with gefitinib, AZ1366 (tan

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Reversing Melanoma Cross-Resistance to BRAF and MEK Inhibitors by Co-Targeting the AKT/mTOR Pathway

肿瘤耐药机制

信号通路靶向治疗

BackgroundThe sustained clinical activity of the BRAF inhibitor vemurafenib (PLX4032/RG7204) in patients with BRAFV600 mutant melanoma is limited primarily by the development of acquired resistance le

Figshare2016-01-18 更新50

Suppression of adaptive responses to targeted cancer therapy by transcriptional repression [RNA-seq]. Homo sapiens

肿瘤耐药机制

转录组药物响应

Large-scale genomic profiling efforts have facilitated the characterization of molecular alterations in cancers and aided the development of targeted kinase inhibitors for a wide array of cancer types

NIAID Data Ecosystem50

PRP4K is a HER2-regulated modifier of taxane sensitivity

癌症药物敏感性

HER2信号通路

The taxanes are used alone or in combination with anthracyclines or platinum drugs to treat breast and ovarian cancer, respectively. Taxanes target microtubules in cancer cells and modifiers of taxane

NIAID Data Ecosystem50

Ploidy variations between secondary resistant and parental soft-tissue sarcoma cell lines.

肿瘤耐药机制

细胞倍性分析

only sensitive cloneonly resistant clone-: absence of allelic imbalancePloidy variations between secondary resistant and parental soft-tissue sarcoma cell lines.

Figshare2015-12-03 更新50

Anthracycline treatment and resistance in four human cancer cell lines (HGU133A)

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