intestinal microbiota and mother's reproductive tract flora in children with Down syndrome Raw sequence reads

Patients with Down syndrome (DS) is often accompanied by increased rate of infections, hypertention, objectivity and gastrointestinal disorders, which are the most common abnormal and have a significant impact on their daily life, the gut microbiota plays an important role in maintaining the gut's homeostasis and improving immunity and has been linked to the development of obesity, hypertension, and colon cancer. However, there are few studies on the intestinal flora and the mother's reproductive tract flora of children with DS in childhood. Therefore, the 16S sequencing technology was used to analyze and explore the intestinal flora of children with DS and the microbial abundance and diversity composition in the mother's reproductive tract.