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Mammary Gland Morphological and Gene Expression Changes Underlying Pregnancy Protection of Breast Cancer Tumorigenesis

ChEBI2011-09-14 更新2026-07-21 收录

乳腺发育与妊娠

乳腺癌发生机制

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-32125 数据链接链接失效反馈

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Mammary Gland Morphological and Gene Expression Changes Underlying Pregnancy Protection of Breast Cancer Tumorigenesis

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2011-09-14

乳腺干细胞调控

乳腺癌发生机制

Mammary gland branching morphogenesis and ductal homeostasis relies on mammary stem cell function for the maintenance of basal and luminal cell compartments. The mechanisms of transcriptional regulati

NIAID Data Ecosystem70

ATM Suppresses SATB1-Induced Malignant Progression in Breast Epithelial Cells

乳腺癌发生机制

细胞表型漂移

SATB1 drives metastasis when expressed in breast tumor cells by radically reprogramming gene expression. Here, we show that SATB1 also has an oncogenic activity to transform certain non-malignant brea

NIAID Data Ecosystem30

EpCAM overexpression prolongs proliferative capacity of primary human breast epithelial cells and supports hyperplastic growth. Homo sapiens

乳腺癌发生机制

EpCAM研究

Background: The Epithelial Cell Adhesion Molecule (EpCAM) has been shown to be strongly expressed in human breast cancer and cancer stem cells and its overexpression has been supposed to support tumor

NIAID Data Ecosystem30

Modeling the MYC-driven normal-to-tumour switch in breast cancer.. Modeling the MYC-driven normal-to-tumour switch in breast cancer.

乳腺癌发生机制

MYC癌基因

The potent MYC oncoprotein is deregulated in many human cancers, including breast carcinoma, and is associated with aggressive disease. To understand the mechanisms and vulnerabilities of MYC-driven b

NIAID Data Ecosystem60

Nanolipoprotein mediated Her2 protein transfection induces malignant transformation in human breast acinar cultures

乳腺癌发生机制

蛋白质转染技术

We describe transcriptomic changes in HMT-3522-S1 cells cultured in the acinar morphogenesis assay in reponse to either empty-nanolipoprotein stimulus, Her2-nanolipoprotien stimulus or control unstimu

NIAID Data Ecosystem30

Mammary Gland Morphological and Gene Expression Changes Underlying Pregnancy Protection of Breast Cancer Tumorigenesis

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