Active DNA demethylation controls transgenerational epigenetic stability. Active DNA demethylation controls transgenerational epigenetic stability

We examined spontaneously occurring variation in DNA methylation in wild type Col-0 plants, together with nrpd1 and ros1 mutants that are all propagated from single-seed descent for 10 generations. Overall design: The samples examined are: Col-0_G1, nrpd1_G1, ros1_G1, Col-0_G10_rep1, Col-0_G10_rep2, Col-0_G10_rep3, Col-0_G10_rep4, Col-0_G10_rep5, nrpd1_G10_rep1, nrpd1_G10_rep2, nrpd1_G10_rep3, nrpd1_G10_rep4, nrpd1_G10_rep5, ros1_G10_rep1, ros1_G10_rep2, ros1_G10_rep3, ros1_G10_rep4, ros1_G10_rep5, Col-0_salt_G10_rep1, Col-0_salt_G10_rep2, Col-0_salt_G10_rep3, Col-0_salt_G10_rep4, Col-0_salt_G10_rep5, nrpd1_salt_G10_rep1, nrpd1_salt_G10_rep2, nrpd1_salt_G10_rep3, nrpd1_salt_G10_rep4, ros1_salt_G10_rep1, ros1_salt_G10_rep2, ros1_salt_G10_rep3, ros1_salt_G10_rep4, ros1_salt_G10_rep5, Col-0_G7, ros1_G7, ros1_salt_G7