PRDM16 Functions as A Compact Myocardium-Enriched Transcription Factor Required to Maintain Compact Myocardial Cardiomyocyte Identity in Left Ventricle (bulk RNA-seq)

Gene expression profiling in whole heart, left ventricle (LV) and right ventricle (RV) of WT and Prdm16 conditional knockout (Prdm16cKO) mouse (Prdm16flox/flox; Xmlc2-Cre) at embryonic day 13.5 (E13.5). Three pairs of whole hearts, four pairs of isolated LV and four pairs of isolated RV from Prdm16cKO and littermate control mice were subject to RNA-seq analysis to identify differentially expressed genes (DEGs) in whole heart, LV and RV of Prdm16cKO mice.本数据集包含胚胎第13.5天（E13.5）的野生型（Wild Type, WT）与Prdm16条件性敲除（Prdm16 conditional knockout, Prdm16cKO）小鼠（基因型为Prdm16flox/flox; Xmlc2-Cre）的全心脏、左心室（Left Ventricle, LV）及右心室（Right Ventricle, RV）的基因表达谱数据。研究人员从Prdm16cKO小鼠及其同窝对照小鼠中采集了3对全心脏样本、4对分离的左心室样本与4对分离的右心室样本，随后对上述样本开展RNA测序（RNA-seq）分析，以鉴定Prdm16cKO小鼠全心脏、左心室及右心室中的差异表达基因（Differentially Expressed Genes, DEGs）。