CCI.net fungal keratitis cases dataset

Patients diagnosed with FK were enrolled from three cities in China between April 2015 and June 2022. The diagnosis was confirmed either by corneal cultures or corneal biopsy. Patients who were over 65 years old, had systemic diseases such as diabetes, autoimmune diseases, thyroid-related diseases, or were pregnant, were excluded. Patients with bacterial, amebic, or other infections confirmed by culture were also excluded. A total of 355 patients were included, comprising 212 from Zhongshan Ophthalmic Center in Guangdong Province, 83 from Xi'an First Hospital in Shanxi Province, and 60 from Guangxi Zhuang Autonomous Region People's Hospital in Guangxi Zhuang Autonomous Region.
There were 5 licensed ophthalmologists using standard processing to grade the image quality. A total of 8697 images were graded as good quality and were further divided into three datasets: a classification dataset (N=7086, including 4255 in the training set, 1413 in the validation set, and 1418 in the test set), ..., Patients diagnosed with FK were enrolled from three cities in China between April 2015 and June 2022. The diagnosis was confirmed either by corneal cultures or corneal biopsy. Patients who were over 65 years old, had systemic diseases such as diabetes, autoimmune diseases, thyroid-related diseases, or were pregnant, were excluded. Patients with bacterial, amebic, or other infections confirmed by culture were also excluded. A total of 355 patients were included, comprising 212 from Zhongshan Ophthalmic Center in Guangdong Province, 83 from Xi'an First Hospital in Shanxi Province, and 60 from Guangxi Zhuang Autonomous Region People's Hospital in Guangxi Zhuang Autonomous Region.There were 5 licensed ophthalmologists using standard processing to grade the image quality. A total of 8697 images were graded as good quality and were further divided into three datasets: a classification dataset (N=7086, including 4255 in the training set, 1413 in the validation set, and 1418 in the test set), a..., , There were 5 licensed ophthalmologists using standard processing to grade the image quality. A total of 8697 images were graded as good quality and were further divided into three datasets: a classification dataset (N=7086, including 4255 in the training set, 1413 in the validation set, and 1418 in the test set), a segmentation dataset (N=56, including 46 in the training set and 10 in the test set), and an external validation set (N=1555, including 1455 to validate the classification model and 100 to validate the segmentation model) (Figure 1).

Clinically, three experienced ophthalmologists from Zhongshan Ophthalmic Center were responsible for ophthalmological research and clinical work. According to the results of fungal culture, each image was divided into five categories. Two ophthalmologists separately classified images of each type of fungal keratitis, and the third ophthalmologist reclassified the images with inconsistent classification results from the first two ophthalmologi...

2015年4月至2022年6月期间，从中国三座城市招募确诊为真菌性角膜炎（Fungal Keratitis，FK）的患者。诊断通过角膜培养或角膜活检予以确认。本研究排除以下患者：年龄超过65岁者，合并糖尿病、自身免疫性疾病、甲状腺相关疾病等全身性疾病者，以及妊娠期女性；同时排除经培养证实为细菌性、阿米巴性或其他感染的患者。最终共纳入355例患者，其中广东省中山眼科中心212例、陕西省西安市第一医院83例、广西壮族自治区人民医院60例。由5名持证眼科医师采用标准化流程对图像质量进行评级。最终共有8697张图像被评定为优质图像，并进一步划分为三个数据集：分类数据集（N=7086，其中训练集4255张、验证集1413张、测试集1418张）、分割数据集（N=56，其中训练集46张、测试集10张）以及外部验证集（N=1555，其中1455张用于分类模型验证、100张用于分割模型验证）（图1）。临床层面，来自中山眼科中心的3名资深眼科医师负责本次研究的眼科相关临床工作。根据真菌培养结果，每张图像被划分为五个类别。由两名眼科医师分别对每类真菌性角膜炎的图像进行分类，若前两名医师的分类结果存在分歧，则由第三名眼科医师进行复核分类。