Endresen1997_SinoatrialActionPotential

This a model from the article:
Chaos in weakly-coupled pacemaker cells.

Endresen LP. J Theor Biol
1997 Jan 7;184(1):41-50 9039399
,
Abstract:

A model of the rabbit sinoatrial action potential is introduced, based on a
model by Morris & Lecar. One cell is described by two nonlinear first-order
ordinary differential equations, with ten constant parameters. The model is much
simpler than most other models in use, but can reproduce perfectly
experimentally recorded action potentials. The dynamics of two coupled cells,
with and without the presence of periodic acetylcholine pulses, shows examples
of bifurcations and strange attractors, mathematical phenomena characterizing
chaotic motion. It remains to be clarified whether such dynamics is actually
observed, for example in the small irregular variations of the normal heart
rate.
This model was taken from the CellML repository
and automatically converted to SBML.
The original model was:
Endresen LP. (1996) - version01

The original CellML model was created by:
Noble, Penny, J

[e-mail]
Oxford University
Department of Physiology, Anatomoy & Genetics
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