Cryo-EM structure of the FB1-bound Lac1-Lip1 complex

Cryo-EM structure of the FB1-bound Lac1-Lip1 complex Descriptor: (2~{R})-2-[2-[(5~{R},6~{R},7~{S},9~{S},11~{R},16~{R},18~{S},19~{S})-19-azanyl-6-[(3~{R})-3-carboxy-5-oxidanyl-5-oxidanylidene-pentanoyl]oxy-5,9-dimethyl-11,16,18-tris(oxidanyl)icosan-7-yl]oxy-2-oxidanylidene-ethyl]butanedioic acid, (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, Ceramide synthase LAC1, ... Authors: Xie, T, Zhang, Z, Fang, Q, Gong, X. Deposit date: 2024-01-26 Release date: 2024-11-27 Last modified: 2025-07-16 Method: ELECTRON MICROSCOPY (3.07 Å) Cite: Mechanism of ceramide synthase inhibition by fumonisin B 1. Structure, 32, 2024