Efficacy of benznidazole (Bz) and posaconazole (Ps) treatments for 7 days (monotherapy or combination) in murine model of acute Trypanosoma cruzi infection1.

1Swiss female (n = 6) weight 20 to 24 g were inoculated with 5×103 trypomastigotes (Ystrain).Treatment was started at 4th day after inoculation followed by 7 daily doses and the drugs were administered orally.*Significant difference in relation to benznidazole monotherapy treatment at same dose.ND – Not detected.