Nek2 bound to hybrid compound 21
收藏Protein Data Bank Japan2023-12-20 更新2026-03-21 收录
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Nek2 bound to hybrid compound 21 Descriptor: 1,2-ETHANEDIOL, 4-(2-AMINO-5-{4-[(DIMETHYLAMINO)METHYL]THIOPHEN-2-YL}PYRIDIN-3-YL)-2-{[(1R,2Z)-4,4,4-TRIFLUORO-1-METHYLBUT-2-EN-1-YL]OXY}BENZAMIDE, SERINE/THREONINE-PROTEIN KINASE NEK2 Authors: Yeoh, S, Innocenti, P, Hoelder, S, Bayliss, R. Deposit date: 2012-01-19 Release date: 2012-04-25 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (2.597 Å) Cite: Design of Potent and Selective Hybrid Inhibitors of the Mitotic Kinase Nek2: Structure-Activity Relationship, Structural Biology, and Cellular Activity. J.Med.Chem., 55, 2012
创建时间:
2012-01-19



