Approach to the Synthesis of Antitumor Quassinoids from Labdane Diterpenes: An Efficient Synthesis of a Picrasane-Related Intermediate
收藏NIAID Data Ecosystem2026-03-06 收录
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The tetracyclic ketal 24, a suitable intermediate for the synthesis of antitumor pentacyclic quassinoids, has been efficiently prepared from communic acids (5a−c), via methyl ketone 9. The synthetic sequence from 9 to 24 consists of 15 steps in 12% overall yield.
创建时间:
2016-08-20



