Highly Diastereoselective Synthesis of Tetrahydropyridines by a C–H Activation–Cyclization–Reduction Cascade
收藏NIAID Data Ecosystem2026-03-07 收录
下载链接：
https://figshare.com/articles/dataset/Highly_Diastereoselective_Synthesis_of_Tetrahydropyridines_by_a_C_H_Activation_Cyclization_Reduction_Cascade/2543548
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资源简介：
A versatile reaction cascade leading to highly substituted
1,2,3,6-tetrahydropyridines
has been developed. It comprises rhodium(I)-catalyzed C–H activation–alkyne
coupling followed by electrocyclization and subsequent acid/borohydride-promoted
reduction. This one-pot procedure affords the target compounds in
up to 95% yield with >95% diastereomeric purity.
创建时间：
2012-03-07
