Prostaglandin E2 (PGE2) Enhances Aged Hematopoietic Stem Cell Function. Prostaglandin E2 (PGE2) Enhances Aged Hematopoietic Stem Cell Function

The purpose of this RNA sequencing dataset was to analyze transcriptional signaling in young and aged murine hematopoietic stem cells when pulsed ex vivo with dimethyl (dm)PGE2. Overall design: RNS sequencing was performed on hematopoietic stem cells isolated from young (n=4) or aged (n=4) mice and pulsed ex vivo with dmPGE2 or vehicle (note: each sample was split in two for matched analysis of dmPGE2 vs vehicle effects).