In eukaryotic chromosomes, the centromere and telomere are two specialized structures that are essential for chromosome stability and segregation. Although centromeres and telomeres often are located

NIAID Data Ecosystem60

Supplementary Material for: Calreticulin as a new histone binding protein in mitotic chromosomes

染色体生物学

蛋白质功能

Calreticulin (CRT) is a multifunctional Ca 2+ -binding protein that mainly functions in the endoplasmic reticulum as a molecular chaperone for newly synthesized proteins. Recently we reported

DataCite Commons2020-09-02 更新50

RAD21-TEV NLS-TEV rescue RNAseq. RAD21-TEV NLS-TEV rescue RNAseq

转录组调控

黏连蛋白功能研究

RNA-seq of and doxycycline treated Rad21-TEV primary neuron transduced with NLS-TEV Overall design: Total of 12 samples analysed; 3 replicates of Rad21-tev primary neurons 24h following doxycyline tre

NIAID Data Ecosystem60

Bacillus subtilis Smc peptide insertion screen

蛋白质筛选

染色体生物学

SMC proteins are ubiquitous factors involved in chromosome segregation and maintenance. We screened the Bacillus subtilis Smc protein for sites that can tolerate the insertion of a short peptide.

NIAID Data Ecosystem50

Structural evidence for Scc4-dependent localization of cohesin loading

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