Data from: Absence of strong signal of background selection affecting nucleotide diversity in Drosophila pseudoobscura
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https://datadryad.org/dataset/doi:10.5061/dryad.sj862
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资源简介:
Nucleotide variation correlates positively with regional rates of
recombination in the genomes of many species, and intensive effort has
been devoted to deciphering the evolutionary forces driving this
association. The effects of sweeps associated with the spread of
advantageous mutations and background selection associated with the
removal of detrimental mutations are exceedingly hard to decouple. Here,
we examine patterns of nucleotide variation in a subset of Drosophila
pseudoobscura genes that are unlikely to have been affected by one extreme
class of selective sweeps, and test for residual signal that may be
attributable to background selection. While our statistical power is low
due to the number of genes fitting our criteria and small numbers of
sequences, the proportion of variation explained by our tests is extremely
low and sometimes opposite in direction of predictions of background
selection. We tentatively conclude that most of the association of
nucleotide variation with recombination rate in this species is probably
not attributable to background selection.
提供机构:
Dryad
创建时间:
2014-01-27



