The relevance results between 21 components and 5 factors.

a)For GRD, RC, PCC, SRRC and BV, positive and negative of value means positive and negative effect contribution respectively. The larger the absolute value, the higher the effect contribution. SIV represents the relative importance and reflects the reliability of corresponding variables.b)After comprehensive comparison, P19, P10, P6, and P4 made the main effect contribution to RBC aggregation (F1); P3 and P17 to platelet aggregation (F2); P13, P12, P10, and P19 to intrinsic clotting activity (F3); P11 to RBC deformability and plasma proteins (F4); P1 to extrinsic clotting activity (F5). Meanwhile, P14, P19, P1, and P15 might have negative effect on F1, F2, F3, and F4, respectively.c)P19 (panaxytriol), P10 (ginsenoside Rb1), P3 (angoroside C), P13 (protocatechualdehyde), P11 (ginsenoside Rd), and P1 (calycosin-7-O-β-D-glucoside) are the core bioactive components promoting blood circulation. P14 is rosmarinic acid. P15 is ononin.The relevance results between 21 components and 5 factors.