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Crystal Structure of the Human vaccinia-related kinase bound to BI-D1870

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Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
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Crystal Structure of the Human vaccinia-related kinase bound to BI-D1870 Descriptor: (7S)-2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimethyl-8-(3-methylbutyl)-7,8-dihydropteridin-6(5H)-one, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... Authors: Counago, R.M, Bountra, C, Arruda, P, Edwards, A.M, Gileadi, O, Structural Genomics Consortium (SGC) Deposit date: 2017-02-20 Release date: 2017-03-22 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2 Å) Cite: Structural characterization of human Vaccinia-Related Kinases (VRK) bound to small-molecule inhibitors identifies different P-loop conformations. Sci Rep, 7, 2017
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2017-02-20
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