Gene expression in colon tissue of rats fed digestion resistant carbohydrates

Conventionally raised and germ-free newly weaned male Sprague-Dawley rats were fed a basal diet or a diet supplemented with digestion resistant carbohydrates in the form of inulin, resistant starch or konjac flour. Gene expression in colon tissue was measured to characterise interaction between food, microbes and host.本实验以常规饲养及无菌的刚断奶雄性斯普拉格-道利（Sprague-Dawley）大鼠为研究对象，将其分为两组，分别饲喂基础饲料，或以菊粉、抗性淀粉、魔芋粉形式添加抗消化碳水化合物的试验饲料。通过检测结肠组织的基因表达，以表征食物、微生物与宿主之间的相互作用。