Comparison of cortical cross-sectional bone parameters at the mid-shaft of femurs between WT and <i>Igf1</i> cKO mice after two-week dietary calcium depletion and/or after one-week dietary calcium repletion.

Results are shown as mean ± SEM. # The control group are mice receiving normal calcium-containing diet throughout. a P<0.001; b P<0.01; c P<0.05; when compared to corresponding WT littermates. P = N.S., not significant, when P>0.05. Comparison of cortical cross-sectional bone parameters at the mid-shaft of femurs between WT and Igf1 cKO mice after two-week dietary calcium depletion and/or after one-week dietary calcium repletion.