mRNA Expression Changes Induced by Myocardial MCU Inhibition
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE62049
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Mitochondrial calcium is an important second-messenger controlling fight-or-flight responses in the heart. The molecular identity of MCU (Mitochondrial Calcium Uniporter) was recently discovered allowing us to test this hypothesis in vivo by expressiing a myocardial delimited dominant negative form of MCU. We queried mRNA expression changes induced by dominant negative MCU expression in the heart. Neonatal (< 24 h) and 6 week old hearts were harvested from mice expressing the dominant negative MCU contruct or wild-type littermates.
创建时间:
2019-02-11



