14-3-3 epsilon is an intracellular component of TNFR2 receptor complex and its activation protects against osteoarthritis [single-cell RNA-seq]

To unravel the relative abundance and distribution of PGRN, TNFR2, and 14-3-3ε mRNA transcripts in different chondrocyte subpopulations, we performed single-cell RNA-seq (scRNA-seq) in chondrocytes isolated from human OA and normal cartilage. scRNA-Seq were performed on the single cell suspension isolated from 3 human normal and 4 human OA cartilage