Genomic and immune profiling of prognostic risk groups in IgM gammopathy reveals novel biomarkers beyond MYD88 L265P
收藏NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE284434
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Bone marrow samples were obtained from each patient and underwent CD19+ enrichment by immunomagnetic beads to obtain a purity of at least 90% to perform targeted next generation sequencing covering 54 lymphoma driver genes. The remaining depleted samples underwent RNA isolation and further quantitative measurement of gene expression by the NanoString nCounter platform using the PanCancer Immune Profiling assay that involved 770 genes. The aim was to analyze transcriptomic signatures in immune cells for each prognostic risk category of IgM gammopathy patients
创建时间：
2025-09-16
