The CRAC channel Orai in an open conformation; H206A gain-of-function mutation

This deposit in the Research Collaboratory for Structural Bioinformatics Protein Data Base (PDB) includes cryogenic electron microscopy data identifying the The CRAC channel Orai in an open conformation; H206A gain-of-function mutation. The main summary display for this entry includes information on the experimental method, protein source, macromolecules and small molecules included in the deposit, and version history and funding identification. Data is provided for download as FASTA sequence format, the Protein Data Bases own PDB format, crystallographic information file (.cif), XML, the EM map, as well as the full validation file in either PDF or XML formats. Additionally, the PDB provides embedded visualization software to display a 3D view of the protein: PDB's Mol* viewer, NGL viewer, and JSmol. PDB provides protein family and gene product annotations, additional details about the experiment parameters, a Protein Feature Viewer (in the Sequence tab) which displays all available features and alignments of known polymer instances, and a genome view which provides graphical summaries of the correspondences between PDB Entity sequences and genomes.

该存档收录于结构生物信息学研究协作实验室蛋白质数据库（PDB），其中包含了通过低温电子显微镜技术获得的 CRAC 通道 Orai 在开放构象下的数据；以及 H206A 增效突变的相关数据。本条目的主要摘要展示包含了实验方法、蛋白质来源、存档中包含的宏分子和低分子物质信息，以及版本历史和资助标识。数据以 FASTA 序列格式、蛋白质数据库自有 PDB 格式、晶体学信息文件（.cif）、XML、电子显微镜图以及 PDF 或 XML 格式的完整验证文件提供下载。此外，PDB 还提供了嵌入式可视化软件，用于展示蛋白质的 3D 视图：PDB 的 Mol* 查看器、NGL 查看器和 JSmol。PDB 提供蛋白质家族和基因产物注释、关于实验参数的额外详细信息、蛋白质特征查看器（位于序列标签中），该查看器展示了所有已知聚合物实例的特征和比对，以及基因组视图，该视图提供了 PDB 实体序列与基因组之间对应关系的图形总结。