Effect of TET deletion on the global DNA methylation status of osteoclasts (RNA-Seq)

Epigenetic regulation is a fundamental mechanism mediating various cellular processes. However, epigenetic mechanisms in osteoclastogenesis remain incompletely understood. We performed RNA-seq analysis to investigate gene expression in osteoclasts derived from wild-type and Tet2Rank–/–; Tet3aRank+/– mice. Examination of RNA expression in 2 cell types.