Overall association between various characteristics of interest and mean BOT-2 score, with and without adjustment for age and sex (N = 37) and concentrations of each of the biochemical predictors (N = 32).

All multivariable models include age and gender as control variables. (*)  =  Adjusted for individual predictors, (#)  =  higher score indicates greater cognition performance. Model 1  =  baseline multivariable model. Model 2  =  Model 1 supplemented with isoprostane-III. Model 3  =  Model 1 supplemented with 8,12-iso-iPF2α-VI isoprostane as predictor. The addition of isoprostane VI did not improve the baseline model.
After adjustment for each of the predictors including cognitive performance, only concentrations of albumin and 8,12-iso-iPF2α-VI isoprostane, among the biochemical measures, were significant predictors in the model explaining the largest variation (Model 3) in the BOT-2 scores; models built for all subjects irrespective of the konzo status.
Overall association between various characteristics of interest and mean BOT-2 score, with and without adjustment for age and sex (N = 37) and concentrations of each of the biochemical predictors (N = 32).