Listing of predicted B. malayi NMT substrates.
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Survey of potential targets for N-terminal glycine myristoylation in B. malayi. Predicted myristoylated proteins in the proteome of C. elegans (145 clusters) were retrieved from MYRbase and used to query the B. malayi genome. Homologs with a BLASTP E-Value −10 were analyzed using the MYR predictor [55] to predict myristoylation sites. Protein sequences that were scored as “Reliable” with a positive score or “Twilight zone” with a negative score were retained and duplicates were discarded. C. elegans homologs that showed any abnormal phenotype in WormBase were marked with *. Unlikely candidates such as multi-pass integral membrane proteins were removed.Listing of predicted B. malayi NMT substrates.
创建时间:
2015-12-02



