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Intrahepatic expression of genes induced by both low and high dose wIFN-α or induced by neither.

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NIAID Data Ecosystem2026-03-09 收录
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https://figshare.com/articles/dataset/_Intrahepatic_expression_of_genes_induced_by_both_low_and_high_dose_wIFN_945_or_induced_by_neither_/1538305
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RNA-Seq data for select genes significantly induced by both low dose (20 μg) and high dose (100 μg) wIFN-α (top 9 rows), or induced by neither (bottom 5 rows). The full list of genes induced by both low dose and high dose wIFN-α (n = 775 genes) is displayed in S8B Table. aFold-change ratio values relative to time-matched placebo animals (n = 5–12) are displayed, with underlining denoting statistical significance (FDR<0.05). Fold-change ratio was calculated as described for Table 2. bHugo symbols are used for gene names. Alternative gene names; CD274: PD-L1, TNFSF10: TRAIL, KLRC1: NKG2A, FCGR3A: CD16, NCAM1: CD56. cFold-change ratios for FASLG at week 3 and PRF1 at week 11 were close to statistical significance (FDR = 0.097 and FDR = 0.062, respectively). W: week. Intrahepatic expression of genes induced by both low and high dose wIFN-α or induced by neither.
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2015-09-09
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