five

Characterization of expression changes in qin by tiling array

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE30061
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Qin, a novel protein comprising amino-terminal E3 ligase and five carboxy terminal Tudor domains, silences transposons and ensures genome stability in the Drosophila germline by promoting antisene piRNA amplification via Aubergine:Ago3 Ping-Pong and preventing futile Aubergine:Aubergine interactions. Extract total ovary RNAs, and using tiling array to test transposon as well as gene expression in wild-type and qin mutant flies. Three biological replicates are used.
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2015-07-08
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