Clinical and laboratory features of mastocytosis patients stratified according to TET2 mutations.

Symbols and Abbreviations: AST, aspartate aminotransferase, LDH, Lactate dehydrogenase, wt, wild-type; NA, not available.*Includes pruritus, flushing, urticaria, and angioedema.†Includes weight loss, fever, chills, and night sweats.‡Includes headache, dizziness/lightheadedness, syncope/presyncope, hypotension, anaphylaxis, palpitation/tachycardia, bronchoconstriction/wheezing, and peptic ulcer disease.§Weight loss of >10% of normal body weight over a period of 6 months or less.IIPalpable splenomegaly or hepatomegaly.¶Lymphadenopathy on palpation or imaging.